Elizabeth Strout has spent most of her career working the same geographical and emotional territory — the coast of Maine, the quiet devastations of marriage and childhood, the specific heaviness of the things people do not say. Olive Kitteridge, My Name Is Lucy Barton, Oh William — each book deepened and extended an artistic project that has become one of the most sustained and coherent in contemporary American fiction. The Things We Never Say, publishing May 5, departs from the Maineverse she has inhabited for decades.

The premise of Homebound, Portia Elan’s debut novel publishing May 5, is structurally unusual: five lives across six centuries are connected by a single computer game. The description places it in the tradition of novels that use a recurring artifact or location to draw disparate historical periods into conversation — the kind of structural device that either unifies the book’s emotional argument or serves as a gimmick the individual sections outgrow.

Douglas Stuart won the Booker Prize for Shuggie Bain, which was a novel about poverty, addiction, and the particular cruelty of the Scottish working class toward those it identifies as different. Young Mungo covered similar territory with similar emotional intensity. Both books were exceptional. Both were also so concentrated on their setting and social milieu that readers who loved them had to wonder what Stuart would do when he moved the frame.

Tayari Jones published An American Marriage in 2018, which won the Women’s Prize for Fiction and became an Oprah’s Book Club selection. It is one of the more precisely realized American novels of the decade — a story about a wrongful conviction and the marriage it destroys that manages to be simultaneously a social novel and an intimate one. The follow-up has been anticipated for years. Kin is appearing on early-year best-books lists before the critical apparatus has fully deployed.

Lessons in Chemistry was one of those novels that accumulated readers over time rather than arriving already famous. It became a word-of-mouth phenomenon, then an Apple TV+ series with Brie Larson, and Bonnie Garmus turned into one of the more closely watched debut authors of recent years. The pressure on her second novel is considerable. The follow-up is centered on a young man hired by Peck & Peck, described as the most prestigious, secretive, and dysfunctional poetry journal in New York.

The Midnight Library sold millions of copies and became the kind of book that appeared in airport bookshops and recovery centers simultaneously. It reached a readership that does not usually track literary fiction releases. Matt Haig’s follow-up to that novel, The Midnight Train, publishing May 26, is described as a sibling work to that book — not a sequel, but set in the same metaphysical territory. The premise trades the infinite library of alternate lives for something more linear: a single train journey between the life someone is living and the life they abandoned, with stops at each significant decision point along the way.